Simparica TRIO Chewables for Dogs and Puppies 22.1–44 lbs (Blue Pack) is formulated for medium dogs and puppies 8 weeks of age and older weighing between 22.1–44 lbs. This Blue color pack, once-monthly, liver-flavored chew contains 24 mg sarolaner, 0.48 mg moxidectin, and 100 mg pyrantel to provide broad parasite protection. It helps prevent heartworm disease, kills fleas, treats and controls roundworms and hookworms, and protects against tick infestations, including deer ticks that may carry Lyme infections. By eliminating fleas, it also helps prevent flea tapeworm (Dipylidium caninum) infections. Given once a month as directed by your veterinarian, it offers accurate, weight-specific protection for medium dogs.

How It Helps

Simparica TRIO works by combining trusted ingredients (sarolaner, moxidectin, and pyrantel) to protect your dog from multiple parasites at once. It provides 100% protection against heartworm disease when given monthly. It starts killing fleas within 4 hours and achieves full effectiveness within 8 hours, helping stop infestations before fleas can lay eggs. It also treats and controls roundworms and hookworms and helps prevent flea tapeworm infections by eliminating fleas. In addition, it protects against six species of ticks (Gulf coast tick, American dog tick, Lone star tick, Black-legged tick or Deer tick, Brown dog tick, and Asian longhorned tick) for a full month, including the deer tick that may carry Lyme disease.

Who it’s for

Your veterinarian can help determine the correct dosage based on your dog’s current weight.

Why Pet Parents Choose It